Which of the following vaccines requires refrigeration for storage?

The Hepatitis B vaccine requires refrigeration for storage. This is because the vaccine contains live attenuated viruses, which need to be kept at specific temperatures to remain effective and stable. Refrigeration helps preserve the integrity of the vaccine's components, ensuring its potency when administered.

In a pharmacy or healthcare setting, it is crucial to maintain the cold chain for vaccines like Hepatitis B to prevent degradation and enhance patient safety. Proper storage conditions include temperatures typically between 2°C and 8°C (36°F to 46°F) for most vaccines, including Hepatitis B.

While some vaccines, such as the Covid-19 vaccine, have specific storage requirements that can vary significantly; some formulations require ultra-cold storage, while others can be refrigerated. The Measles vaccine, which is also a live attenuated vaccine, requires refrigeration but is often stored in a slightly warmer range than Hepatitis B. The Shingles vaccine, particularly the recombinant zoster vaccine, needs to be stored in refrigeration as well. However, the key point for the context of this question focuses on the Hepatitis B vaccine being a vaccine that consistently requires refrigeration for safety and effectiveness.